Chronic Pancreatitis Causes : The most accepted hypothesis regarding the pathogenesis of chronic pancreatitis is the sentinel acute pancreatitis event (sape) hypothesis, in which an initial insult or injury to the pancreas results in acute pancreatitis.. The most common cause of acute pancreatitis is having gallstones. Feb 14, 2020 · most cases of chronic pancreatitis are associated with drinking excessive amounts of alcohol over a long period of time. Feb 01, 2018 · chronic pancreatitis: Chronic pancreatitis can also cause diabetes. Jan 03, 2021 · chronic pancreatitis causes constant or regular bouts of stomach pain. Chronic pancreatitis can also cause diabetes. It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption.it is a disease process characterized by irreversible damage to the pancreas as distinct from reversible … Feb 01, 2018 · chronic pancreatitis: Chronic pancreatitis cause